Yep! It think something like 700 moose are killed annually on the roads in Alaska, we've come close to hitting them countless times. It's rare any kind of vehicle comes out less than totalled after hitting a moose, and many people die from the collisions too.
We used to have that problem in New Hampshire too, when it's dark all you can see are the legs in the headlights because the moose are so tall. People would hit them at night right around the knee area and the rest of the moose would come falling through the roof of their cars. That's a whole lot of animal falling on your head....